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An analysis of DNA methylation in human adipose tissue reveals differential modification of obesity genes before and after gastric bypass and weight loss

BACKGROUND: Environmental factors can influence obesity by epigenetic mechanisms. Adipose tissue plays a key role in obesity-related metabolic dysfunction, and gastric bypass provides a model to investigate obesity and weight loss in humans. RESULTS: Here, we investigate DNA methylation in adipose t...

詳細記述

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書誌詳細
出版年:Genome Biol
主要な著者: Benton, Miles C, Johnstone, Alice, Eccles, David, Harmon, Brennan, Hayes, Mark T, Lea, Rod A, Griffiths, Lyn, Hoffman, Eric P, Stubbs, Richard S, Macartney-Coxson, Donia
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301800/
https://ncbi.nlm.nih.gov/pubmed/25651499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0569-x
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