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TORC1 Inhibition Induces Lipid Droplet Replenishment in Yeast

Lipid droplets (LDs) are intracellular structures that regulate neutral lipid homeostasis. In mammals, LD synthesis is inhibited by rapamycin, a known inhibitor of the mTORC1 pathway. In Saccharomyces cerevisiae, LD dynamics are modulated by the growth phase; however, the regulatory pathways involve...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Madeira, Juliana B., Masuda, Claudio A., Maya-Monteiro, Clarissa M., Matos, Gabriel Soares, Montero-Lomelí, Mónica, Bozaquel-Morais, Bruno L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301715/
https://ncbi.nlm.nih.gov/pubmed/25512609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01314-14
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