Population Testing for Cancer Predisposing BRCA1/BRCA2 Mutations in the Ashkenazi-Jewish Community: A Randomized Controlled Trial

BACKGROUND: Technological advances raise the possibility of systematic population-based genetic testing for cancer-predisposing mutations, but it is uncertain whether benefits outweigh disadvantages. We directly compared the psychological/quality-of-life consequences of such an approach to family hi...

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Publicat a:J Natl Cancer Inst
Autors principals: Manchanda, Ranjit, Loggenberg, Kelly, Sanderson, Saskia, Burnell, Matthew, Wardle, Jane, Gessler, Sue, Side, Lucy, Balogun, Nyala, Desai, Rakshit, Kumar, Ajith, Dorkins, Huw, Wallis, Yvonne, Chapman, Cyril, Taylor, Rohan, Jacobs, Chris, Tomlinson, Ian, McGuire, Alistair, Beller, Uziel, Menon, Usha, Jacobs, Ian
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301703/
https://ncbi.nlm.nih.gov/pubmed/25435541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/dju379
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