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Myostatin and IGF-I signaling in end-stage human heart failure: a qRT-PCR study

BACKGROUND: Myostatin (Mstn) is a key regulator of heart metabolism and cardiomyocyte growth interacting tightly with insulin-like growth factor I (IGF-I) under physiological conditions. The pathological role of Mstn has also been suggested since Mstn protein was shown to be upregulated in the myoca...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Baán, Júlia Aliz, Varga, Zoltán V, Leszek, Przemyslaw, Kuśmierczyk, Mariusz, Baranyai, Tamás, Dux, László, Ferdinandy, Péter, Braun, Thomas, Mendler, Luca
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301667/
https://ncbi.nlm.nih.gov/pubmed/25591711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-014-0365-0
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