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Fascin1-Dependent Filopodia are Required for Directional Migration of a Subset of Neural Crest Cells

Directional migration of neural crest (NC) cells is essential for patterning the vertebrate embryo, including the craniofacial skeleton. Extensive filopodial protrusions in NC cells are thought to sense chemo-attractive/repulsive signals that provide directionality. To test this hypothesis, we gener...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Boer, Elena F., Howell, Elizabeth D., Schilling, Thomas F., Jette, Cicely A., Stewart, Rodney A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301650/
https://ncbi.nlm.nih.gov/pubmed/25607881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004946
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