A Genome-Wide Investigation of MicroRNA Expression Identifies Biologically-Meaningful MicroRNAs That Distinguish between High-Risk and Low-Risk Intraductal Papillary Mucinous Neoplasms of the Pancreas

BACKGROUND: Intraductal papillary mucinous neoplasms (IPMNs) are pancreatic ductal adenocarcinoma (PDAC) precursors. Differentiating between high-risk IPMNs that warrant surgical resection and low-risk IPMNs that can be monitored is a significant clinical problem, and we sought to discover a panel o...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Permuth-Wey, Jennifer, Chen, Y. Ann, Fisher, Kate, McCarthy, Susan, Qu, Xiaotao, Lloyd, Mark C., Kasprzak, Agnieszka, Fournier, Michelle, Williams, Vonetta L., Ghia, Kavita M., Yoder, Sean J., Hall, Laura, Georgeades, Christina, Olaoye, Funmilayo, Husain, Kazim, Springett, Gregory M., Chen, Dung-Tsa, Yeatman, Timothy, Centeno, Barbara Ann, Klapman, Jason, Coppola, Domenico, Malafa, Mokenge
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301643/
https://ncbi.nlm.nih.gov/pubmed/25607660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116869
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