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Trastuzumab increases the sensitivity of HER2-amplified human gastric cancer cells to oxaliplatin and cisplatin by affecting the expression of telomere-associated proteins

HER2 amplification occurs in ~20% of gastric cancer (GC) cases; however, in gastric and gastroesophageal junction cancer with HER2 gene amplification, trastuzumab in combination with cisplatin (DDP)-based chemotherapy has been reported to improve the oncological outcome. The aim of the present study...

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Publicat a:Oncol Lett
Autors principals: LIU, YONGPING, LING, YANG, QI, QIUFENG, ZHU, MING, WAN, MEIZHEN, ZHANG, YAPING, ZHANG, CHANGSONG
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301541/
https://ncbi.nlm.nih.gov/pubmed/25624920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2014.2793
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