Inhibition of dipeptidyl peptidase-IV enzyme activity protects against myocardial ischemia-reperfusion injury in rats

BACKGROUND: We investigated whether attenuating dipeptidyl peptidase-IV (DPP4) enzyme activity protected rat heart from ischemia-reperfusion (IR) injury (40-min left anterior descending coronary artery ligation followed by 72 h reperfusion). METHODS AND RESULTS: Adult male Fischer 344 rats (n = 24)...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Chua, Sarah, Lee, Fan-Yen, Tsai, Tzu-Hsien, Sheu, Jiunn-Jye, Leu, Steve, Sun, Cheuk-Kwan, Chen, Yung-Lung, Chang, Hsueh-Wen, Chai, Han-Tan, Liu, Chu-Feng, Lu, Hung-I, Yip, Hon-Kan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301397/
https://ncbi.nlm.nih.gov/pubmed/25496837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-014-0357-0
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