Interaction of Infectious Spleen and Kidney Necrosis Virus ORF119L with PINCH Leads to Dominant-Negative Inhibition of Integrin-Linked Kinase and Cardiovascular Defects in Zebrafish

Infectious spleen and kidney necrosis virus (ISKNV) is the type species of the Megalocytivirus genus, Iridoviridae family, causing a severe systemic disease with high mortality in mandarin fish (Siniperca chuatsi) in China and Southeast Asia. At present, the pathogenesis of ISKNV infection is still...

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Vydáno v:J Virol
Hlavní autoři: Yuan, Ji-Min, He, Bai-Liang, Yang, Lu-Yun, Guo, Chang-Jun, Weng, Shao-Ping, Li, Shengwen Calvin, He, Jian-Guo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301147/
https://ncbi.nlm.nih.gov/pubmed/25355883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01955-14
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