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T Cell Epitope Clustering in the Highly Immunogenic BZLF1 Antigen of Epstein-Barr Virus

Polymorphism in the human leukocyte antigen (HLA) loci ensures that the CD8(+) T cell response to viruses is directed against a diverse range of antigenic epitopes, thereby minimizing the impact of virus escape mutation across the population. The BZLF1 antigen of Epstein-Barr virus is an immunodomin...

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Publicado en:J Virol
Autores principales: Rist, Melissa J., Neller, Michelle A., Burrows, Jacqueline M., Burrows, Scott R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301143/
https://ncbi.nlm.nih.gov/pubmed/25355876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02642-14
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