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Entry Mechanisms of Herpes Simplex Virus 1 into Murine Epidermis: Involvement of Nectin-1 and Herpesvirus Entry Mediator as Cellular Receptors

Skin keratinocytes represent a primary entry site for herpes simplex virus 1 (HSV-1) in vivo. The cellular proteins nectin-1 and herpesvirus entry mediator (HVEM) act as efficient receptors for both serotypes of HSV and are sufficient for disease development mediated by HSV-2 in mice. How HSV-1 ente...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Petermann, Philipp, Thier, Katharina, Rahn, Elena, Rixon, Frazer J., Bloch, Wilhelm, Özcelik, Semra, Krummenacher, Claude, Barron, Martin J., Dixon, Michael J., Scheu, Stefanie, Pfeffer, Klaus, Knebel-Mörsdorf, Dagmar
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301110/
https://ncbi.nlm.nih.gov/pubmed/25320325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02917-14
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