Plasmid deficiency in urogenital isolates of Chlamydia trachomatis reduces infectivity and virulence in a mouse model

We hypothesized that the plasmid of urogenital isolates of Chlamydia trachomatis would modulate infectivity and virulence in a mouse model. To test this hypothesis, we infected female mice in the respiratory or urogenital tract with graded doses of a human urogenital isolate of C. trachomatis, serov...

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Vydáno v:Pathog Dis
Hlavní autoři: Sigar, Ira M., Schripsema, Justin H., Wang, Yibing, Clarke, Ian N., Cutcliffe, Lesley T., Seth‐Smith, Helena M.B., Thomson, Nicholas R., Bjartling, Carina, Unemo, Magnus, Persson, Kenneth, Ramsey, Kyle H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
Molecular Pathogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300952/
https://ncbi.nlm.nih.gov/pubmed/24022847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/2049-632X.12086
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