DEK is a potential marker for aggressive phenotype and irinotecan-based therapy response in metastatic colorectal cancer

BACKGROUND: DEK is a transcription factor involved in stabilization of heterochromatin and cruciform structures. It plays an important role in development and progression of different types of cancer. This study aims to analyze the role of DEK in metastatic colorectal cancer. METHODS: Baseline DEK e...

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Dades bibliogràfiques
Publicat a:BMC Cancer
Autors principals: Martinez-Useros, Javier, Rodriguez-Remirez, Maria, Borrero-Palacios, Aurea, Moreno, Irene, Cebrian, Arancha, Gomez del Pulgar, Teresa, del Puerto-Nevado, Laura, Vega-Bravo, Ricardo, Puime-Otin, Alberto, Perez, Nuria, Zazo, Sandra, Senin, Clara, Fernandez-Aceñero, Maria J, Soengas, Maria S, Rojo, Federico, Garcia-Foncillas, Jesus
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300837/
https://ncbi.nlm.nih.gov/pubmed/25515240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-965
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