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BGLF4 Kinase Modulates the Structure and Transport Preference of the Nuclear Pore Complex To Facilitate Nuclear Import of Epstein-Barr Virus Lytic Proteins

BGLF4 kinase, the only Ser/Thr protein kinase encoded by the Epstein-Barr virus (EBV) genome, phosphorylates multiple viral and cellular substrates to optimize the cellular environment for viral DNA replication and the nuclear egress of nucleocapsids. Previously, we found that nuclear targeting of B...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Chang, Chou-Wei, Lee, Chung-Pei, Su, Mei-Tzu, Tsai, Ching-Hwa, Chen, Mei-Ru
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300756/
https://ncbi.nlm.nih.gov/pubmed/25410863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02880-14
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