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Characterization of 2-amino-1-methyl-6-phenylimidazo[4,5b]pyridine at androgen receptor: mechanistic support for its role in prostate cancer

2-amino-1-methyl-6-phenylimidazo[4,5b]pyridine (PhIP) is a dietary mutagenic carcinogen that has been shown not only to induce the formation of DNA adducts, but is capable of inducing tumors in the colon, mammary, and prostate glands. The normal development and maturation of the prostate gland, as w...

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Опубликовано в: :Am J Cancer Res
Главные авторы: Glass-Holmes, Mashunté, Aguilar, Byron J, Gragg, Richard D, Darling-Reed, Selina, Goodman, Carl B
Формат: Artigo
Язык:Inglês
Опубликовано: e-Century Publishing Corporation 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300711/
https://ncbi.nlm.nih.gov/pubmed/25628930
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