Abrogation of the Interferon Response Promotes More Efficient Human Cytomegalovirus Replication

The effect of abrogating the interferon (IFN) response on human cytomegalovirus (HCMV) replication was investigated using primary human cells engineered to block either the production of or the response to type I IFNs. In IFN-deficient cells, HCMV produced larger plaques and spread and replicated mo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: McSharry, Brian P., Forbes, Simone K., Avdic, Selmir, Randall, Richard E., Wilkinson, Gavin W. G., Abendroth, Allison, Slobedman, Barry
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2014
Gaiak:
Virus-Cell Interactions
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300662/
https://ncbi.nlm.nih.gov/pubmed/25392213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02988-14
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