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Abrogation of the Interferon Response Promotes More Efficient Human Cytomegalovirus Replication
The effect of abrogating the interferon (IFN) response on human cytomegalovirus (HCMV) replication was investigated using primary human cells engineered to block either the production of or the response to type I IFNs. In IFN-deficient cells, HCMV produced larger plaques and spread and replicated mo...
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Publicado no: | J Virol |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4300662/ https://ncbi.nlm.nih.gov/pubmed/25392213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02988-14 |
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