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Abrogation of the Interferon Response Promotes More Efficient Human Cytomegalovirus Replication

The effect of abrogating the interferon (IFN) response on human cytomegalovirus (HCMV) replication was investigated using primary human cells engineered to block either the production of or the response to type I IFNs. In IFN-deficient cells, HCMV produced larger plaques and spread and replicated mo...

詳細記述

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書誌詳細
出版年:J Virol
主要な著者: McSharry, Brian P., Forbes, Simone K., Avdic, Selmir, Randall, Richard E., Wilkinson, Gavin W. G., Abendroth, Allison, Slobedman, Barry
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300662/
https://ncbi.nlm.nih.gov/pubmed/25392213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02988-14
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