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Specificity of Coxsackievirus B3 Interaction with Human, but Not Murine, Decay-Accelerating Factor: Replacement of a Single Residue within Short Consensus Repeat 2 Prevents Virus Attachment

Many coxsackievirus B (CVB) isolates bind to human decay-accelerating factor (DAF) as well as to the coxsackievirus and adenovirus receptor (CAR). However, the virus does not interact with murine DAF. To understand why CVB3 binds specifically to human DAF, we constructed a series of chimeric molecul...

Полное описание

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Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Pan, Jieyan, Zhang, Lili, Organtini, Lindsey J., Hafenstein, Susan, Bergelson, Jeffrey M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300647/
https://ncbi.nlm.nih.gov/pubmed/25392210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02798-14
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