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Two Distinct Sets of NS2A Molecules Are Responsible for Dengue Virus RNA Synthesis and Virion Assembly

Flavivirus nonstructural protein 2A (NS2A) plays important roles in both viral RNA synthesis and virion assembly. The molecular details of how the NS2A protein modulates the two distinct events have not been defined. To address this question, we have performed a systematic mutagenesis of NS2A using...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Xie, Xuping, Zou, Jing, Puttikhunt, Chunya, Yuan, Zhiming, Shi, Pei-Yong
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300643/
https://ncbi.nlm.nih.gov/pubmed/25392211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02882-14
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