CXCL16 suppresses liver metastasis of colorectal cancer by promoting TNF-α-induced apoptosis by tumor-associated macrophages

BACKGROUND: Inhibition of metastasis through upregulation of immune surveillance is a major purpose of chemokine gene therapy. In this study, we focused on a membrane-bound chemokine CXCL16, which has shown a correlation with a good prognosis for colorectal cancer (CRC) patients. METHODS: We generat...

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Publicado en:BMC Cancer
Autores principales: Kee, Ji-Ye, Ito, Aya, Hojo, Shozo, Hashimoto, Isaya, Igarashi, Yoshiko, Tsuneyama, Koichi, Tsukada, Kazuhiro, Irimura, Tatsuro, Shibahara, Naotoshi, Takasaki, Ichiro, Inujima, Akiko, Nakayama, Takashi, Yoshie, Osamu, Sakurai, Hiroaki, Saiki, Ikuo, Koizumi, Keiichi
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300614/
https://ncbi.nlm.nih.gov/pubmed/25495942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-949
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