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Recurrent Low-Dose Chemotherapy to Inhibit and Oxygenate Head and Neck Tumors

A lack of strategy to counteract hypoxia (pO(2)< 10–15 mmHg) and technique to repeatedly measure tumor pO(2) has restricted therapeutic optimization. We report the results obtained with an innovative anti-angiogenic strategy of recurrent low-dose (metronomic) chemotherapy to modulate hypoxia and...

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Detalhes bibliográficos
Publicado no:Adv Exp Med Biol
Main Authors: Khan, Nadeem, Hou, Huagang, Hodge, Sassan, Kuppusamy, Muthulakshmi, Chen, Eunice Y., Eastman, Alan, Kuppusamy, Periannan, Swartz, Harold M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300520/
https://ncbi.nlm.nih.gov/pubmed/24729221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-0620-8_14
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