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Zirconium Ions Up-Regulate the BMP/SMAD Signaling Pathway and Promote the Proliferation and Differentiation of Human Osteoblasts

Zirconium (Zr) is an element commonly used in dental and orthopedic implants either as zirconia (ZrO(2)) or in metal alloys. It can also be incorporated into calcium silicate-based ceramics. However, the effects of in vitro culture of human osteoblasts (HOBs) with soluble ionic forms of Zr have not...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Chen, Yongjuan, Roohani-Esfahani, Seyed-Iman, Lu, ZuFu, Zreiqat, Hala, Dunstan, Colin R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300214/
https://ncbi.nlm.nih.gov/pubmed/25602473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113426
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