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Zirconium Ions Up-Regulate the BMP/SMAD Signaling Pathway and Promote the Proliferation and Differentiation of Human Osteoblasts

Zirconium (Zr) is an element commonly used in dental and orthopedic implants either as zirconia (ZrO(2)) or in metal alloys. It can also be incorporated into calcium silicate-based ceramics. However, the effects of in vitro culture of human osteoblasts (HOBs) with soluble ionic forms of Zr have not...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chen, Yongjuan, Roohani-Esfahani, Seyed-Iman, Lu, ZuFu, Zreiqat, Hala, Dunstan, Colin R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300214/
https://ncbi.nlm.nih.gov/pubmed/25602473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113426
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