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Cellular epigenetics: topochronology of progressive "spontaneous" transformation of cells under growth constraint.

Early passages of NIH 3T3 cells yield about 10 transformed foci for every 10(5) cells seeded after the cells multiply to confluence in a standardized 2-week assay. The question arose whether more cells would give rise to foci if given more time for their development. This question could not be answe...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Chow, M, Yao, A, Rubin, H
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1994
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42996/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8290570/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.2.599
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