Asymptomatic HIV-infected Individuals on Antiretroviral Therapy Exhibit Impaired Lung CD4(+) T-Cell Responses to Mycobacteria

Rationale: HIV-infected persons on antiretroviral therapy (ART) remain at higher risk of pulmonary tuberculosis (TB) than HIV-uninfected individuals. This increased susceptibility may be caused by impairment of alveolar macrophage (AM) function and/or mycobacteria-specific alveolar CD4(+) T-cell res...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Jambo, Kondwani C., Banda, Dominic H., Afran, Louise, Kankwatira, Anstead M., Malamba, Rose D., Allain, Theresa J., Gordon, Stephen B., Heyderman, Robert S., Russell, David G., Mwandumba, Henry C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299580/
https://ncbi.nlm.nih.gov/pubmed/25225948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201405-0864OC
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