Comparative Study of 6-Mercaptopurine Metabolism in Human Leukemic Leukocytes and L1210 Cells

Leukocytes from patients with leukemia and L1210 cells from mice were examined for the rate of formation and cellular concentration of phosphoribosylpyrophosphate, the rate of thioinosinic acid formation, and a number of selected enzymes involved in purine nucleotide synthesis. The amount of thioino...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Higuchi, Tomihiko, Nakamura, Toru, Uchino, Haruto, Wakisaka, Gyoichi
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1977
Subjects:
Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429957/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/921247/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.12.4.518
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