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Phenotypic bistability in Escherichia coli's central carbon metabolism

Fluctuations in intracellular molecule abundance can lead to distinct, coexisting phenotypes in isogenic populations. Although metabolism continuously adapts to unpredictable environmental changes, and although bistability was found in certain substrate-uptake pathways, central carbon metabolism is...

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Bibliographic Details
Published in:Mol Syst Biol
Main Authors: Kotte, Oliver, Volkmer, Benjamin, Radzikowski, Jakub L, Heinemann, Matthias
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299493/
https://ncbi.nlm.nih.gov/pubmed/24987115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20135022
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