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Cell lineage analysis in human brain using endogenous retroelements

Somatic mutations occur during brain development and are increasingly implicated as a cause of neurogenetic disease. However, the patterns in which somatic mutations distribute in the human brain are unknown. We used high-coverage whole-genome sequencing of single neurons from a normal individual to...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Evrony, Gilad D., Lee, Eunjung, Mehta, Bhaven K., Benjamini, Yuval, Johnson, Robert M., Cai, Xuyu, Yang, Lixing, Haseley, Psalm, Lehmann, Hillel S., Park, Peter J., Walsh, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299461/
https://ncbi.nlm.nih.gov/pubmed/25569347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.12.028
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