Beta-Lactamase Effect on Ampicillin Treatment of Haemophilus influenzae B Bacteremia and Meningitis in Infant Rats

Intraperitoneal injections of 250 mg of ampicillin per kg every 6 h for 30 h sterilized the blood and cerebrospinal fluid of infant rats infected with either a β-lactamase-containing strain of Haemophilus influenzae type b or a strain lacking the enzyme. However, a single injection of 100 mg/kg ster...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Moxon, E. Richard, Medeiros, Antone A., O'Brien, Thomas F.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1977
Assuntos:	Pharmacology and Therapeutics
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429946/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/303497/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.12.4.461
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