A TISSUE BIOMARKER BASED MODEL THAT IDENTIFIES PATIENTS WITH A HIGH RISK OF DISTANT METASTASIS AND DIFFERENTIAL SURVIVAL BY LENGTH OF ANDROGEN DEPRIVATION THERAPY IN RTOG PROTOCOL 92-02

PURPOSE: To examine the relationship between the expression of 7 promising apoptotic/cell proliferation proteins (Ki-67, p53, MDM2, bcl-2, bax, p16, and Cox-2) and risk of distant metastasis (DM). EXPERIMENTAL DESIGN: RTOG 92-02 compared external beam radiotherapy (EBRT) to ~70 Gy+short term androge...

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Veröffentlicht in:Clin Cancer Res
Hauptverfasser: Pollack, Alan, Dignam, James J, Diaz, Dayssy A, Wu, Qian, Stoyanova, Radka, Bae, Kyounghwa, Dicker, Adam P, Sandler, Howard, Hanks, Gerald E, Feng, Felix Y
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299458/
https://ncbi.nlm.nih.gov/pubmed/25294917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-0075
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