Allelic expression mapping across cellular lineages to establish impact of non-coding SNPs

Most complex disease-associated genetic variants are located in non-coding regions and are therefore thought to be regulatory in nature. Association mapping of differential allelic expression (AE) is a powerful method to identify SNPs with direct cis-regulatory impact (cis-rSNPs). We used AE mapping...

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Udgivet i:Mol Syst Biol
Main Authors: Adoue, Veronique, Schiavi, Alicia, Light, Nicholas, Almlöf, Jonas Carlsson, Lundmark, Per, Ge, Bing, Kwan, Tony, Caron, Maxime, Rönnblom, Lars, Wang, Chuan, Chen, Shu-Huang, Goodall, Alison H, Cambien, Francois, Deloukas, Panos, Ouwehand, Willem H, Syvänen, Ann-Christine, Pastinen, Tomi
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2014
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299376/
https://ncbi.nlm.nih.gov/pubmed/25326100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20145114
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