Inhibition of soluble epoxide hydrolase modulates inflammation and autophagy in obese adipose tissue and liver: Role for omega-3 epoxides

Soluble epoxide hydrolase (sEH) is an emerging therapeutic target in a number of diseases that have inflammation as a common underlying cause. sEH limits tissue levels of cytochrome P450 (CYP) epoxides derived from omega-6 and omega-3 polyunsaturated fatty acids (PUFA) by converting these antiinflam...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: López-Vicario, Cristina, Alcaraz-Quiles, José, García-Alonso, Verónica, Rius, Bibiana, Hwang, Sung H., Titos, Esther, Lopategi, Aritz, Hammock, Bruce D., Arroyo, Vicente, Clària, Joan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299190/
https://ncbi.nlm.nih.gov/pubmed/25550510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1422590112
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