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Genes suppressed by DNA methylation in non-small cell lung cancer reveal the epigenetics of epithelial–mesenchymal transition

BACKGROUND: DNA methylation is associated with aberrant gene expression in cancer, and has been shown to correlate with therapeutic response and disease prognosis in some types of cancer. We sought to investigate the biological significance of DNA methylation in lung cancer. RESULTS: We integrated t...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Lin, Steven H, Wang, Jing, Saintigny, Pierre, Wu, Chia-Chin, Giri, Uma, Zhang, Jing, Menju, Toshi, Diao, Lixia, Byers, Lauren, Weinstein, John N, Coombes, Kevin R, Girard, Luc, Komaki, Ritsuko, Wistuba, Ignacio I, Date, Hiroshi, Minna, John D, Heymach, John V
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298954/
https://ncbi.nlm.nih.gov/pubmed/25486910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-1079
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