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Molecular regulation of the expression of leptin by hypoxia in human coronary artery smooth muscle cells

BACKGROUND: Leptin, produced mainly by white adipose tissue, is a hormone that promotes vascular smooth muscle cell (VSMC) migration and proliferation, a process involved in the pathophysiology of atherosclerosis. Leptin expression in human coronary artery smooth cell (HCASMC) is induced by hypoxia....

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Pubblicato in:J Biomed Sci
Autori principali: Chiu, Chiung-Zuan, Wang, Bao-Wei, Shyu, Kou-Gi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298872/
https://ncbi.nlm.nih.gov/pubmed/25573199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-014-0109-8
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