Can quaternary ammonium methacrylates inhibit matrix MMPs and cathepsins?

OBJECTIVE: Dentin matrices release ICTP and CTX fragments during collagen degradation. ICTP fragments are known to be produced by MMPs. CTX fragments are thought to come from cathepsin K activity. The purpose of this study was to determine if quaternary methacrylates (QAMs) can inhibit matrix MMPs a...

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Bibliographic Details
Published in:Dent Mater
Main Authors: Tezvergil-Mutluay, Arzu, Agee, Kelli A., Mazzoni, Annalisa, Carvalho, Ricardo M., Carrilho, Marcela, Tersariol, Ivarne L., Nascimento, Fabio D., Imazato, Satoshi, Tjäderhane, Leo, Breschi, Lorenzo, Tay, Franklin R, Pashley, David H.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298465/
https://ncbi.nlm.nih.gov/pubmed/25467953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dental.2014.10.006
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