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Comparative Nephrotoxicities of Netilmicin and Gentamicin in Rats

The relative nephrotoxicities of netilmicin (Sch 20569) and gentamicin were compared in rats at doses of 30, 60, 90, and 120 mg/kg per day for 15 days. Both drugs caused proteinuria and a decrease in urine osmolality; however, netilmicin produced significantly less changes at all doses than gentamic...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Luft, Friedrich C., Yum, Moo Nahm, Kleit, Stuart A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1976
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429846/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1008542/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.10.5.845
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