Heparin-coated cardiopulmonary bypass circuits selectively deplete the pattern recognition molecule ficolin-2 of the lectin complement pathway in vivo

The complement system can be activated via the lectin pathway by the recognition molecules mannose-binding lectin (MBL) and the ficolins. Ficolin-2 exhibits binding against a broad range of ligands, including biomaterials in vitro, and low ficolin-2 levels are associated with increased risk of infec...

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Bibliografiske detaljer
Udgivet i:Clin Exp Immunol
Main Authors: Hein, E, Munthe-Fog, L, Thiara, A S, Fiane, A E, Mollnes, T E, Garred, P
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2015
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298406/
https://ncbi.nlm.nih.gov/pubmed/25174443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12446
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