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SIRT1 expression is associated with a poor prognosis, whereas DBC1 is associated with favorable outcomes in gastric cancer

Clinical trials of histone deacetylase (HDAC) inhibitors as antitumor therapy have been conducted for gastric cancer. Expression of SIRT1, a class III HDAC, is related to poor prognosis in some malignancies. We investigated the correlation between SIRT1 expression and progression and prognosis of ga...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Noguchi, Akira, Kikuchi, Keiji, Zheng, Huachuan, Takahashi, Hiroyuki, Miyagi, Yohei, Aoki, Ichiro, Takano, Yasuo
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298382/
https://ncbi.nlm.nih.gov/pubmed/25146318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.310
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