Sustained in vivo signaling by long-lived IL-2 induces prolonged increases of regulatory T cells

Regulatory T cells (Tregs) expressing FOXP3 are essential for the maintenance of self-tolerance and are deficient in many common autoimmune diseases. Immune tolerance is maintained in part by IL-2 and deficiencies in the IL-2 pathway cause reduced Treg function and an increased risk of autoimmunity....

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Autoimmun
Main Authors: Bell, Charles J.M., Sun, Yongliang, Nowak, Urszula M., Clark, Jan, Howlett, Sarah, Pekalski, Marcin L., Yang, Xin, Ast, Oliver, Waldhauer, Inja, Freimoser-Grundschober, Anne, Moessner, Ekkehard, Umana, Pablo, Klein, Christian, Hosse, Ralf J., Wicker, Linda S., Peterson, Laurence B.
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298360/
https://ncbi.nlm.nih.gov/pubmed/25457307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2014.10.002
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados