HMG-CoA reductase inhibitory activity and phytocomponent investigation of Basella alba leaf extract as a treatment for hypercholesterolemia

The enzyme 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase is the key enzyme of the mevalonate pathway that produces cholesterol. Inhibition of HMG-CoA reductase reduces cholesterol biosynthesis in the liver. Synthetic drugs, statins, are commonly used for the treatment of hypercholestero...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Baskaran, Gunasekaran, Salvamani, Shamala, Ahmad, Siti Aqlima, Shaharuddin, Noor Azmi, Pattiram, Parveen Devi, Shukor, Mohd Yunus
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298350/
https://ncbi.nlm.nih.gov/pubmed/25609924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S75056
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