Toll-Like Receptor 3 Is Critical for Coxsackievirus B4-Induced Type 1 Diabetes in Female NOD Mice

Group B coxsackieviruses (CVBs) are involved in triggering some cases of type 1 diabetes mellitus (T1DM). However, the molecular mechanism(s) responsible for this remain elusive. Toll-like receptor 3 (TLR3), a receptor that recognizes viral double-stranded RNA, is hypothesized to play a role in viru...

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Dettagli Bibliografici
Pubblicato in:Endocrinology
Autori principali: McCall, Kelly D., Thuma, Jean R., Courreges, Maria C., Benencia, Fabian, James, Calvin B.L., Malgor, Ramiro, Kantake, Noriko, Mudd, William, Denlinger, Nathan, Nolan, Bret, Wen, Li, Schwartz, Frank L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2015
Soggetti:
Diabetes-Insulin-Glucagon-Gastrointestinal
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298321/
https://ncbi.nlm.nih.gov/pubmed/25422874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-2006
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