Differential Effects of 5-Methylmercapto-2′-Deoxyuridine on the Replication of Herpes Simplex Virus Type 1 in Two Cell Systems

5-Methylmercapto-2′-deoxyuridine (MeMUdR), a structural analogue of thymidine (TdR), inhibits herpes simplex virus type 1 production in mouse L (Lb) cells at concentrations that are not inhibitory to viral growth in monkey kidney (CV-1) cells. It is moderately toxic to Lb cells but not to CV-1 cells...

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Autores principales: Hardi, Robert, Hughes, R. G., Ho, Y. K., Chadha, K. C., Bardos, T. J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1976
Materias:
Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC429814/
https://ncbi.nlm.nih.gov/pubmed/185952
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