Protective Role for Caspase-11 during Acute Experimental Murine Colitis

Activation of the noncanonical inflammasome, mediated by caspase-11, serves as an additional pathway for the production of the proinflammatory cytokines IL-1β and IL-18. Noncanonical inflammasome activity occurs during host defense against Gram-negative bacteria and in models of acute septic shock....

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Oficjalska, Katarzyna, Raverdeau, Mathilde, Aviello, Gabriella, Wade, Siobhan C., Hickey, Ana, Sheehan, Katherine M., Corr, Sinead C., Kay, Elaine W., O’Neill, Luke A., Mills, Kingston H. G., Creagh, Emma M.
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2015
Assuntos:
Innate Immunity and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298125/
https://ncbi.nlm.nih.gov/pubmed/25548224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400501
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