Comparative study of the effect of rivaroxaban and fondaparinux on monocyte’s coagulant activity and cytokine release

OBJECTIVES: Tissue factor (TF) exposed on activated monocytes and macrophages is involved in thrombosis through activation of factor X and cytokine release, responsible for inflammation and thrombosis. We investigated the effect of two anti-factor Xa drugs: rivaroxaban, a direct anti-Xa inhibitor, a...

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Veröffentlicht in:Exp Hematol Oncol
Hauptverfasser: Laurent, Marc, Joimel, Ulrich, Varin, Rémi, Cazin, Lionel, Gest, Caroline, Le-Cam-Duchez, Veronique, Jin, Jian, Liu, Jielin, Vannier, Jean-Pierre, Lu, He, Soria, Jeannette, Li, Hong, Soria, Claudine
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298120/
https://ncbi.nlm.nih.gov/pubmed/25601900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2162-3619-3-30
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