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Evolutionary and structural annotation of disease-associated mutations in human aminoacyl-tRNA synthetases
BACKGROUND: Mutation(s) in proteins are a natural byproduct of evolution but can also cause serious diseases. Aminoacyl-tRNA synthetases (aaRSs) are indispensable components of all cellular protein translational machineries, and in humans they drive translation in both cytoplasm and mitochondria. Mu...
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| Publié dans: | BMC Genomics |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4298046/ https://ncbi.nlm.nih.gov/pubmed/25476837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-1063 |
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