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Progressive glucose stimulation of islet beta cells reveals a transition from segregated to integrated modular functional connectivity patterns

Collective beta cell activity in islets of Langerhans is critical for the supply of insulin within an organism. Even though individual beta cells are intrinsically heterogeneous, the presence of intercellular coupling mechanisms ensures coordinated activity and a well-regulated exocytosis of insulin...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Markovič, Rene, Stožer, Andraž, Gosak, Marko, Dolenšek, Jurij, Marhl, Marko, Rupnik, Marjan Slak
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297961/
https://ncbi.nlm.nih.gov/pubmed/25598507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07845
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