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Progressive glucose stimulation of islet beta cells reveals a transition from segregated to integrated modular functional connectivity patterns

Collective beta cell activity in islets of Langerhans is critical for the supply of insulin within an organism. Even though individual beta cells are intrinsically heterogeneous, the presence of intercellular coupling mechanisms ensures coordinated activity and a well-regulated exocytosis of insulin...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Markovič, Rene, Stožer, Andraž, Gosak, Marko, Dolenšek, Jurij, Marhl, Marko, Rupnik, Marjan Slak
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297961/
https://ncbi.nlm.nih.gov/pubmed/25598507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07845
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