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Ethanol-induced oxidant stress modulates hepatic autophagy and proteasome activity

In this review, we describe research findings on the effects of alcohol exposure on two major catabolic systems in liver cells: the ubiquitin–proteasome system (UPS) and autophagy. These hydrolytic systems are not unique to liver cells; they exist in all eukaryotic tissues and cells. However, becaus...

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Dettagli Bibliografici
Pubblicato in:Redox Biol
Autori principali: Donohue, Jr., Terrence M., Thomes, Paul G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297932/
https://ncbi.nlm.nih.gov/pubmed/25462063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2014.10.006
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