Early Depletion of Primordial Germ Cells in Zebrafish Promotes Testis Formation

As complete absence of germ cells leads to sterile males in zebrafish, we explored the relationship between primordial germ cell (PGC) number and sexual development. Our results revealed dimorphic proliferation of PGCs in the early zebrafish larvae, marking the beginning of sexual differentiation. W...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Tzung, Keh-Weei, Goto, Rie, Saju, Jolly M., Sreenivasan, Rajini, Saito, Taiju, Arai, Katsutoshi, Yamaha, Etsuro, Hossain, Mohammad Sorowar, Calvert, Meredith E.K., Orbán, László
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297871/
https://ncbi.nlm.nih.gov/pubmed/25434820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.10.011
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