Early Depletion of Primordial Germ Cells in Zebrafish Promotes Testis Formation

As complete absence of germ cells leads to sterile males in zebrafish, we explored the relationship between primordial germ cell (PGC) number and sexual development. Our results revealed dimorphic proliferation of PGCs in the early zebrafish larvae, marking the beginning of sexual differentiation. W...

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Udgivet i:Stem Cell Reports
Main Authors: Tzung, Keh-Weei, Goto, Rie, Saju, Jolly M., Sreenivasan, Rajini, Saito, Taiju, Arai, Katsutoshi, Yamaha, Etsuro, Hossain, Mohammad Sorowar, Calvert, Meredith E.K., Orbán, László
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297871/
https://ncbi.nlm.nih.gov/pubmed/25434820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.10.011
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