CYP2J2 overexpression attenuates nonalcoholic fatty liver disease induced by high-fat diet in mice

Cytochrome P-450 epoxygenase-derived epoxyeicosatrienoic acids (EETs) exert diverse biological activities, which include potent vasodilatory, anti-inflammatory, antiapoptotic, and antioxidatant effects, and cardiovascular protection. Liver has abundant epoxygenase expression and high levels of EET p...

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Publicat a:Am J Physiol Endocrinol Metab
Autors principals: Chen, Guangzhi, Xu, Renfan, Zhang, Shasha, Wang, Yinna, Wang, Peihua, Edin, Matthew L., Zeldin, Darryl C., Wang, Dao Wen
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297779/
https://ncbi.nlm.nih.gov/pubmed/25389366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00366.2014
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