Substrate Inhibition of Beta-Lactamases, a Method for Predicting Enzymatic Stability of Cephalosporins

Selected cephalosporins, including cefamandole, cephaloridine, cephaloglycin, and cefoxitin, were examined for their ability to inhibit the enzymatic activity of and act as substrates for beta-lactamases produced by Enterobacter cloacae and Staphylococcus aureus. Enzyme inhibition was determined by...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Mahoney, David F., Koppel, G. A., Turner, J. R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1976
Assuntos:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429774/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/984790/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.10.3.470
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