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Prenatal Nicotine Alters the Developmental Neurotoxicity of Postnatal Chlorpyrifos Directed Toward Cholinergic Systems: Better, Worse, or Just “Different?”

This study examines whether prenatal nicotine exposure sensitizes the developing brain to subsequent developmental neurotoxicity evoked by chlorpyrifos, a commonly-used insecticide. We gave nicotine to pregnant rats throughout gestation at a dose (3 mg/kg/day) producing plasma levels typical of smok...

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Détails bibliographiques
Publié dans:Brain Res Bull
Auteurs principaux: Slotkin, Theodore A., Seidler, Frederic J.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297693/
https://ncbi.nlm.nih.gov/pubmed/25510202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2014.12.003
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