Single molecule–sensitive probes for imaging RNA in live cells

To visualize native or non-engineered RNA in live cells with single-molecule sensitivity, we developed multiply labeled tetravalent RNA imaging probes (MTRIPs). When delivered with streptolysin O into living human epithelial cancer cells and primary chicken fibroblasts, MTRIPs allowed the accurate i...

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Bibliografiske detaljer
Udgivet i:Nat Methods
Main Authors: Santangelo, Philip J, Lifland, Aaron W, Curt, Paul, Sasaki, Yukio, Bassell, Gary J, Lindquist, Michael E, Crowe, James E
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297622/
https://ncbi.nlm.nih.gov/pubmed/19349979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1316
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